The U.S. Food and Drug Administration (FDA) has not approved the use of any dermal fillers during pregnancy, due to insufficient data on how they might affect a developing infant.
Similarly, though there are no reports that indicate problems when pregnant women receive botulinum toxin (e.g., Botox), the FDA has not conducted any clinical studies to determine how it affects pregnant women or their developing babies.
Because of this lack of research, many doctors are hesitant to give either treatment during pregnancy. They are also wary about administering either Botox or dermal fillers after your first trimester, when your baby’s organs are developing rapidly.
However, the American Society of Plastic Surgeons (ASPS) notes that it is likely safe to have these treatments done in the second or third trimester, after 16 weeks gestation.